Shrestha Lab at CPDR
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Precision Oncology
BAP1 Haploinsufficiency Predicts a Distinct Immunogenic Class of Malignant Peritoneal Mesothelioma
Malignant peritoneal mesothelioma (PeM) is a rare and fatal cancer originating from the abdominal lining. Our study revealed that BAP1 could serve as a prognostic and predictive biomarker for immunotherapy in PeM.
Raunak Shrestha
,
N Nabavi
,
Y Lin
,
F Mo
,
S Anderson
,
S Volik
,
H H Adomat
,
D Lin
,
H Xue
,
X Dong
,
R Shukin
,
RH Bell
,
B McConeghy
,
A Haegert
,
S Brahmbhatt
,
E Li
,
HZ Oo
,
A Hurtado-Coll
,
L Fazli
,
J Zhou
,
Y McConnell
,
A McCart
,
A Lowy
,
GB Morin
,
T Chen
,
M Daugaard
,
SC Sahinalp
,
F Hach
,
S Le Bihan
,
ME Gleave
,
Y Wang
,
A Churg
,
CC Collins
Feb 7, 2019
PDF
Dataset
DOI
Journal
PubMed
Dataset2
Research Highlight
HIT'nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology
An algorithm to identify cancer driver genes in individual cancer patients by measuring the influence of gene alterations on perturbing transcriptional networks.
Raunak Shrestha
,
E Hodzic
,
T Sauerwald
,
P Dao
,
K Wang
,
J Yeung
,
S Anderson
,
F Vandin
,
G Haffari
,
CC Collins
,
SC Sahinalp
Jul 18, 2017
PDF
Code
Slides
Video
DOI
Journal
PubMed
Video2
Blurb
HIT'nDRIVE: Multi-driver gene prioritization based on hitting time
Raunak Shrestha
,
E Hodzic
,
J Yeung
,
K Wang
,
T Sauerwald
,
P Dao
,
S Anderson
,
H Beltran
,
MA Rubin
,
CC Collins
,
G Haffari
,
SC Sahinalp
Apr 1, 2014
PDF
Code
Video
DOI
Journal