Shrestha Lab at CPDR
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Cancer
Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks
We introduce a novel combinatorial method, cd-CAP, for simultaneous detection of connected subnetworks of an interaction network where genes exhibit conserved alteration patterns across tumor samples.
E Hodzic
,
Raunak Shrestha
,
K Zhu
,
K Cheng
,
CC Collins
,
SC Sahinalp
Feb 5, 2019
PDF
Code
Dataset
DOI
Journal
PubMed
HIT'nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology
An algorithm to identify cancer driver genes in individual cancer patients by measuring the influence of gene alterations on perturbing transcriptional networks.
Raunak Shrestha
,
E Hodzic
,
T Sauerwald
,
P Dao
,
K Wang
,
J Yeung
,
S Anderson
,
F Vandin
,
G Haffari
,
CC Collins
,
SC Sahinalp
Jul 18, 2017
PDF
Code
Slides
Video
DOI
Journal
PubMed
Video2
Blurb
BIRC6-targeting as potential therapy for advanced, enzalutamide-resistant prostate cancer
ISU Luk
,
Raunak Shrestha
,
H Xue
,
F Zhang
,
D Lin
,
A Haegert
,
R Wu
,
X Dong
,
CC Collins
,
A Zoubeidi
,
ME Gleave
,
PW Gout
,
Y Wang
Sep 23, 2016
DOI
Journal
PubMed
Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer
AW Wyatt
,
F Mo
,
K Wang
,
B McConeghy
,
S Brahmbhatt
,
L Jong
,
DM Mitchell
,
RL Johnston
,
A Haegert
,
E Li
,
J Liew
,
J Yeung
,
Raunak Shrestha
,
A Lapuk
,
A McPherson
,
R Shukin
,
RH Bell
,
S Anderson
,
J Bishop
,
A Hurtado-Coll
,
H Xiao
,
AM Chinnaiyan
,
R Mehra
,
D Lin
,
Y Wang
,
L Fazli
,
ME Gleave
,
S Volik
,
CC Collins
Aug 26, 2014
PDF
DOI
Journal
PubMed
A Meta-Analysis Approach for Characterizing Pan-Cancer Mechanisms of Drug Sensitivity in Cell Lines
K Wang
,
Raunak Shrestha
,
AW Wyatt
,
A Reddy
,
J Lehar
,
Y Wang
,
A Lapuk
,
CC Collins
Jul 18, 2014
DOI
Journal
PubMed
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