Cancer

Pathway and network analysis of more than 2,500 whole cancer genomes
Feb 5, 2020
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BAP1 Haploinsufficiency Predicts a Distinct Immunogenic Class of Malignant Peritoneal Mesothelioma
Malignant peritoneal mesothelioma (PeM) is a rare and fatal cancer originating from the abdominal lining. Our study revealed that BAP1 could serve as a prognostic and predictive biomarker for immunotherapy in PeM.
Feb 7, 2019
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BAP1 Haploinsufficiency Predicts a Distinct Immunogenic Class of Malignant Peritoneal Mesothelioma
Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks
We introduce a novel combinatorial method, cd-CAP, for simultaneous detection of connected subnetworks of an interaction network where genes exhibit conserved alteration patterns across tumor samples.
Feb 5, 2019
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Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks
HIT'nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology
An algorithm to identify cancer driver genes in individual cancer patients by measuring the influence of gene alterations on perturbing transcriptional networks.
Jul 18, 2017
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HIT'nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology
BIRC6-targeting as potential therapy for advanced, enzalutamide-resistant prostate cancer
Sep 23, 2016
DOI Journal PubMed
Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer
Aug 26, 2014
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A Meta-Analysis Approach for Characterizing Pan-Cancer Mechanisms of Drug Sensitivity in Cell Lines
Jul 18, 2014
DOI Journal PubMed